PubMed Health⌕ Search

PubMed · 6524704

A simplified method for hand-made oblique graphical reconstructions.

Abstract

The present paper deals with a convenient, manual method for making oblique graphical reconstructions from serial sections. The method is based on a projection on the plane of drawing of a three-dimensional coordinate system, which is submitted to two successive and predetermined spatial rotations. Restriction to two rotations simplifies the mathematical approach to a coordinate transformation from a three-dimensional into a two-dimensional system. The resulting formulae, which are quite easily applied, lead to a quick visualization procedure.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

H Claeys, P Aerts. 1984. A simplified method for hand-made oblique graphical reconstructions.. https://doi.org/10.1002/ar.1092100416

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Clinical pharmacokinetic data of racemic drugs obtained by the indirect method following precolumn diastereomer formation: is the influence of racemization during chiral derivatization significant?

This report reviews the stereoselective data of a number of racemic drugs (n = 17) obtained from indirect chiral method (via diastereomer formation) in comparison to similar data generated by the application of a direct chiral method. While it was noted that the indirect method still continued to be used to characterize the stereoselective disposition of racemic drugs, the present review critically evaluates the issue of racemization that has the potential to skew the stereoselective data obtained from the indirect method. The review describes various remedies to counter and/or minimize the impact of racemization on the final outcome of the stereoselective analysis by the indirect method. On the basis of this review it could be concluded that the indirect method is a viable and important tool for gathering stereoselective data of racemic drugs used in medical practice as well for those racemic drugs still in discovery and developmental stages.

Methods↗