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PubMed · 6526877

New thermionic detector utilizing orthogonal nebulization for capillary column liquid chromatography.

J C Gluckman·M Novotny
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Abstract

A new version of the previously studied phosphorus-sensitive, dual-flame thermionic detector has been developed for microcolumn liquid chromatography. The total column effluent is orthogonally nebulized and aspirated directly into a primary air-hydrogen diffusion flame. Phosphorus compounds with molecular weights extending beyond 500 a.m.u. are then selectively detected by measuring the conductivity of the secondary flame in the presence of a rubidium silicate bead. The sensitivity was found to be 1.36 X 10(-11) g phosphorus/sec at the maximum of a Gaussian peak, and the signal increased linearly with concentration over 2 orders of magnitude for dilute samples. Possible mechanisms accounting for the negative orientation of the signal and for the limited dynamic range are discussed.

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Chemical PhenomenaChemistry, PhysicalChromatography, LiquidMolecular WeightJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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J C Gluckman, M Novotny. 1984-11-30. New thermionic detector utilizing orthogonal nebulization for capillary column liquid chromatography.. https://doi.org/10.1016/s0021-9673(01)97726-x

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