Mononuclear cell collection using various techniques.

Abstract

During the last 15 months, 609 mononuclear cell collections were performed. Lymphocytapheresis and monocytapheresis provides cells for in vitro research studies, investigational transfusion studies and as therapeutic procedures. Automated leukapheresis procedures yields from 1.0-1.5 X 10(9) lymphocytes per liter blood processed. Monocyte yields generally 1/10 of the lymphocyte yields in both lymphocytapheresis and monocytapheresis procedures. Donors had very few reactions, and post collection CBC's showed no significant abnormalities. Mononuclear cell donation appears to have no risk to the normal donor.