Protein and platelet interactions with polymer surfaces.

D R Absolom; W Zingg; C J Van Oss; A W Neumann

doi:10.3109/10731198409118834

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Protein and platelet interactions with polymer surfaces.

D R Absolom·W Zingg·C J Van Oss·A W Neumann

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Abstract

An attempt is made to develop an understanding of the basic mechanism governing the interaction of the major blood proteins and cells with polymer surfaces with a focus on thermodynamic approach. It is believed that such investigations may be helpful to provide a rational for the design of suitable cardiovascular prosthetic materials and to choose materials in such a way that adsorption of certain proteins eg. 'fibrinogen' is thermodynamically unfavourable compared to adsorption of other proteins eg. 'albumin'.

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Adsorption Biocompatible Materials Blood Platelets Blood Proteins Electricity Humans Kinetics Models, Biological Platelet Adhesiveness Polymers Prostheses and Implants Prosthesis Design Rheology Surface Properties Thermodynamics Journal Article Research Support, Non-U.S. Gov't

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D R Absolom, W Zingg, C J Van Oss, A W Neumann. Protein and platelet interactions with polymer surfaces.. https://doi.org/10.3109/10731198409118834

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