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Fatal hyperpyrexia after withdrawal of levodopa.

G P Sechi·F Tanda·R Mutani
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Abstract

We studied a patient affected with idiopathic Parkinson's disease and levodopa-induced dyskinesias. Fatal hyperpyrexia followed simultaneous levodopa withdrawal and a decrease in the dosage of diphenhydramine. The clinical features were those of the neuroleptic malignant syndrome. The rapid decrease in dopaminergic activity may have been important in causing the syndrome.

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Basal Ganglia DiseasesDyskinesia, Drug-InducedHumansLevodopaMaleMiddle AgedParkinson DiseaseSubstance Withdrawal SyndromeCase ReportsJournal Article

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BibTeXRIS

G P Sechi, F Tanda, R Mutani. 1984. Fatal hyperpyrexia after withdrawal of levodopa.. https://doi.org/10.1212/wnl.34.2.249

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