Protein C level at birth.

B Polack; P Pouzol; J Amiral; L Kolodie

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PubMed · 6549231

Protein C level at birth.

B Polack·P Pouzol·J Amiral·L Kolodie

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Abstract

The protein C level was determined, on cord blood, for 30 healthy newborns by electro-immuno assay using a monospecific antiserum. For the newborns the mean level of protein C related antigen is about one third of normal adults' mean level. There is a good correlation between Protein C related antigen and prothrombin related antigen. The low level of these vitamin-K-dependent proteins is probably a consequence of partial liver immaturity at birth. Using two-dimensional immuno-electrophoresis we were unable to detect subcarboxylated forms of protein C. However these abnormal forms could be seen in vitamin-K deficiencies of neonates.

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Administration, Oral Adult Age Factors Anticoagulants Antigens Blood Coagulation Factors Blood Proteins Female Fetal Blood Glycoproteins Humans Immunoelectrophoresis, Two-Dimensional Infant, Newborn Injections, Intravenous Protein C Prothrombin Vitamin K Vitamin K Deficiency Journal Article

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B Polack, P Pouzol, J Amiral, L Kolodie. 1984-10-31. Protein C level at birth.. https://pubmed.ncbi.nlm.nih.gov/6549231/

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