The complement system in pregnancy.

B R Adelsberg

doi:10.1111/j.1600-0897.1983.tb00251.x

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PubMed · 6556018

The complement system in pregnancy.

B R Adelsberg

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Abstract

Maternal recognition of fetal antigens is well-documented. Antibodies directed against fetal antigens are the rule rather than the exception. Maternal antibodies seem to bind fetal antigens at the placental level and apparently activate the complement system even in normal pregnancy, yet multiple studies confirm an increase in C1q, C4, C3 and CH50 levels in pregnancy and an absence of complement activation. More sensitive assays and a broadened concept of the timing of crucial immunologic events may lead to a greater understanding of the importance of the complement system in pregnancy.

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Cell Membrane Complement Activating Enzymes Complement Activation Complement C3-C5 Convertases Complement Pathway, Alternative Complement Pathway, Classical Complement System Proteins Eclampsia Female Fetal Blood Fetus Humans Pregnancy Comparative Study Journal Article

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B R Adelsberg. The complement system in pregnancy.. https://doi.org/10.1111/j.1600-0897.1983.tb00251.x

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