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PubMed · 664189

Transmissible murine colonic hyperplasia.

S W Barthold·G L Coleman·R O Jacoby·E M Livestone·A M Jonas
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Abstract

After exposure to a variant of Citrobacter freundii, suckling and adult mice developed transmissible murine colonic hyperplasia of the same degree of severity. Mucosal hyperplasia was most severe 2 to 3 weeks after inoculation and then regressed. Suckling mice had a high mortality because of secondary inflammatory and erosive changes. Severe hyperplasia was characterized by mitotic activity along the entire crypt column and surface mucosa.

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AnimalsCitrobacterColitisColonColonic DiseasesEnterobacteriaceae InfectionsFemaleHyperplasiaIntestinal MucosaMaleMiceRodent DiseasesComparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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S W Barthold, G L Coleman, R O Jacoby, E M Livestone, A M Jonas. 1978. Transmissible murine colonic hyperplasia.. https://doi.org/10.1177/030098587801500209

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