PubMed · 6646012
Oxygen: our major carcinogen?
Abstract
Evidence has accumulated implicating that atmospheric oxygen can be considered as an important environmental mutagen, whose action can be potentiated by a variety of environmental factors. Under normal conditions oxygen genotoxicity is largely prevented by a cellular antioxygenic defense system, which must be extremely efficient, but might not be entirely safe. A better understanding of this defense system may help to suggest how the incidence of carcinogenesis can be minimized.
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H Joenje. 1983. Oxygen: our major carcinogen?. https://doi.org/10.1016/0306-9877(83)90033-6
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