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Structural studies on pyrrolomycins C, D and E.

M Koyama·N Ezaki·T Tsuruoka·S Inouye
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Abstract

Pyrrolomycins C, D and E are new members of the pyrrolomycin group of antibiotics produced by an Actinosporangium sp. The structures of pyrrolomycins C and D were determined to be 2,3-dichloro-5-(3',5'-dichloro-2'-hydroxybenzoyl)pyrrole and 2,3,4-trichloro-5-(3',5'-dichloro-2'-hydroxybenzoyl)pyrrole, respectively, by means of spectroscopic and synthetic approaches while that of pyrrolomycin E was shown to be 5-chloro-2-(3',5'-dichloro-2'-hydroxyphenyl)-3-nitropyrrole by spectroscopic data.

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Anti-Bacterial AgentsMagnetic Resonance SpectroscopyMass SpectrometryPyrrolesStreptomycetaceaeStructure-Activity RelationshipJournal Article

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M Koyama, N Ezaki, T Tsuruoka, S Inouye. 1983. Structural studies on pyrrolomycins C, D and E.. https://doi.org/10.7164/antibiotics.36.1483

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