[Simple lung function studies; assessment of effects].

E J Duiverman

Home/Archive/PubMed

PubMed · 6670093

[Simple lung function studies; assessment of effects].

E J Duiverman

View original source ↗Export metadata ↓

Abstract

In pediatric practice PEF and FEV1 measurements offer suitable information about the presence of bronchial obstruction. In the out-patient clinic PEF measurements can be performed with a Wright Peak Flow meter. Evaluation of symptoms and treatment at home can be done with a mini Wright Peak Flow meter and a diary card. Flow volume registration offers no essential extra information over spirometry. The severity of bronchoconstriction can be assessed by measuring the reversibility after a bronchodilator. Airway responsiveness to non-allergic stimuli can be determined by the histamine threshold and exercise testing. During an exacerbation of asthma PCO2 is increased due to disturbed ventilation and is a good measure for the severity of the condition. Blood gas measurements indicate the degree of disturbance in gas exchange and are therefore important to measure, especially during acute periods of bronchial obstruction.

Explore related subjects

Airway Obstruction Blood Gas Analysis Child Child, Preschool Humans Lung Lung Diseases, Obstructive Maximal Expiratory Flow-Volume Curves Peak Expiratory Flow Rate Plethysmography, Whole Body Respiratory Function Tests Spirometry English Abstract Journal Article

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

E J Duiverman. 1983. [Simple lung function studies; assessment of effects].. https://pubmed.ncbi.nlm.nih.gov/6670093/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2008

Thyroid involvement with Langerhans cell histiocytosis in a 3-year-old male.

We report on the thyroid involvement with Langerhans cell histiocytosis (LCH) in a 3-year-old male. The patient presented with goiter and primary hypothyroidism. His goiter caused life-threatening airway obstruction. He developed locally invasive disease 4 years after his response to LCH therapy. LCH should be suspected as a cause of goiter and thyroidectomy is recommended.

Airway Obstruction↗

PubMed2007

Potential mechanisms connecting asthma, esophageal reflux, and obesity/sleep apnea complex--a hypothetical review.

Obstructive sleep apnea (OSA) and asthma are potentially linked at several levels. The pathophysiology of these two conditions seems to overlap significantly, as airway obstruction, inflammation, obesity, and several other factors are implicated in the development of both diseases. Gastroesophageal reflux disease (GERD), cardiovascular complications, obesity itself, and the underlying inflammatory processes are all complex contributory factors that provide hypothetical links. Furthermore, a collateral rise in prevalence of both OSA and asthma has been noticed during the past few years, occurring in association with the emerging epidemic of obesity, a common risk factor for both conditions. OSA and asthma share many other risk factors as well. We propose a hypothetical OSA-asthma relationship that has implications on the diagnosis and management of patients presenting with either condition singly. Clinicians should be aware that OSA might complicate asthma management. Based on this hypothesis, we suggest that the treatment of the individual patient who experiences both asthma and OSA needs to be multidisciplinary and comprehensive. This hypothetical association of asthma and OSA, though described anecdotally, has not been systematically studied. In particular, the influence of continuous positive airway pressure therapy (for sleep apnea) on asthma outcomes (such as quality of life, steroid utilization, emergency room visits) and fatality needs to be studied further.

Airway Obstruction↗

PubMed2007

Managing isolated subglottic juvenile xanthogranuloma without tracheostomy: case report and review of literature.

Juvenile Xanthogranuloma (JXG) is a dendritic cell related histiocytic disorder which usually presents in the first year of life as a solitary cutaneous granuloma. Isolated presentation in the upper airway is very rare but can result in severe respiratory distress, especially in young children. We present the case of a 5-month-old male with an isolated subglottic JXG lesion. Endoscopic excision provided symptomatic relief and avoided the need for tracheostomy. The lesion has completely resolved 17 months later. Surgical excision without tracheostomy was the treatment of choice in two of the four additional cases of upper airway JXG presented in the literature. JXG has an excellent prognosis with spontaneous regression over time. Histology alone is frequently inadequate to differentiate JXG from the more common Langerhans Cell Histiocytosis (LCH), which carries a much less favorable prognosis. The evolving field of immunohistochemistry provides an essential tool to establish the correct diagnosis. The typical phenotype of JXG is Factor XIIIa+/Fascin+/CD68+/CD163+/CD14+/CD1a-/S100-.

Airway Obstruction↗