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PubMed · 6672101

Differences in some erythroid regulatory parameters between two inbred mouse strains.

C D Dunn·L Gibson
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Abstract

Normal erythropoiesis in inbred CBA/Tr x CBA/Tr mice is shown to be associated with higher rates of red blood cell production and destruction than in age-matched, but significantly larger, C57Bl6/Tr x C57Bl6/Tr mice. As expected from these observations, serum Ep titers were significantly higher in the CBA/Tr mice than in the C57Bl6/Tr mice. These differences, which appear to result from variations in the operating point for erythropoiesis, can explain the different in vitro erythropoietin sensitivities of hematopoietic tissue from these two mouse strains.

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AnimalsDeoxyuridineErythrocyte AgingErythropoiesisErythropoietinFemaleFetusLiverMaleMiceMice, Inbred C57BLMice, Inbred CBAPregnancyComparative StudyJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.

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C D Dunn, L Gibson. 1983. Differences in some erythroid regulatory parameters between two inbred mouse strains.. https://doi.org/10.1002/stem.5530010501

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