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On-line high-performance liquid affinity chromatography-high-performance liquid chromatography analysis of monomeric ribonucleoside compounds in biological fluids.

E Hagemeier·K Kemper·K S Boos·E Schlimme
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Abstract

We describe an on-line multi-dimensional column chromatography system. It consists of a high-performance liquid affinity chromatography perfractionation column for cis-diol compounds and a series-connected reversed-phase high-performance liquid chromatography system for the analysis of ribonucleosides. This on-line procedure allows the rapid and direct analysis of methylated ribonucleic acid catabolites in biological fluids (serum, urine) and therefore might be useful in pathobiochemistry.

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Chemical PhenomenaChemistryChromatography, AffinityChromatography, High Pressure LiquidHumansMethylationRibonucleosidesJournal ArticleResearch Support, Non-U.S. Gov't

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E Hagemeier, K Kemper, K S Boos, E Schlimme. 1983-12-30. On-line high-performance liquid affinity chromatography-high-performance liquid chromatography analysis of monomeric ribonucleoside compounds in biological fluids.. https://doi.org/10.1016/s0021-9673(00)91643-1

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