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PubMed · 6684065

[Pregnancy and hyperprolactinemia].

G Hoffmann·R H Ackermann·J Happ·O Hey·K Pollow
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Abstract

After endocrinological and radiological evaluation of a hyperprolactinemia 13 patients became pregnant under bromocriptine therapy. In two of these patients a selective adenomectomy was performed by the transphenoidal route because of a prolactin (PRL) secreting adenoma. In 12 patients the pregnancy was not complicated. The serum PRL levels were different but mostly in a normal range. The control of x-ray and visual field in patients with a rapid increase of the PRL levels did not result in a tumor recurrence. After a normal course of the serum PRL concentrations one patient with a microadenoma developed suddenly a chiasma syndrome in the 31th week of gestation. The further evaluation resulted in a pituitary tumor with suprasellar extension. The discrepancy between the radiological result and the normal serum PRL levels was explained by a hemorrhage into the adenoma. After the operation the chiasma syndrome was reversible within a short period. Altogether, the course of the pregnancies was not complicated. We did not see fetal malformations. Post partum the sella x-ray of all patients did not reveal any significant changes so far.

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AdenomaAdultBromocriptineFemaleHumansInfertility, FemalePituitary NeoplasmsPregnancyProlactinJournal Article

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BibTeXRIS

G Hoffmann, R H Ackermann, J Happ, O Hey, K Pollow. 1983. [Pregnancy and hyperprolactinemia].. https://doi.org/10.1055/s-0029-1210245

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