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PubMed · 6709914

Validation of a CT method for flow determination. Work in progress.

D F Guthaner·M Nassi·B Bradley
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Abstract

The dynamic computed tomographic (DCT) method of flow determination is based on the application of venoarterial indicator dilution curves as they reflect flow. Using a simple model consisting of a tube and a single mixing chamber, experimental parameters were optimized in a controlled manner to achieve ideal mixing for flow determination. Under these ideal conditions, and using 16 consecutive 3-second scans of an 8-mm thick section, tube diameters of 8 mm and 20 mm, and flow range of 0.7-2.7 liters per minute, the accuracy of the CT method of flow determination was good (17% error). There was a correlation coefficient of 0.85 between measured flow (FM) and calculated flow (FC), and the paired t-test for FM and FC indicated that there was no statistically significant difference (P = .25). The DCT method of flow determination has been validated in this experiment preliminary to its application to flow characterization in blood vessels in the animal model.

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Blood Flow VelocityModels, AnatomicModels, CardiovascularRheologyTomography, X-Ray ComputedJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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D F Guthaner, M Nassi, B Bradley. 1984. Validation of a CT method for flow determination. Work in progress.. https://doi.org/10.1148/radiology.151.2.6709914

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