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PubMed · 6735650

Conjunctival epithelial wound healing.

H S Geggel·J Friend·R A Thoft
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Abstract

In vivo conjunctival epithelial healing in albino rabbits was investigated by light microscopy following both n-heptanol and trephined conjunctival wounding. Reepithelialization occurred faster following n-heptanol treatment (3 days) versus trephination (6-7 days). No goblet cells were present in the migrating epithelium during reepithelialization. After 1 day of wounding, goblet cells disappeared several millimeters peripheral to the wound margin in both types of wounds. Goblet cells first reappeared peripherally 1 week after wounding before they appeared in the central wound area. These observations indicate that a large area of conjunctival epithelium surrounding a wound is involved with repair of that wound. Since the goblet cell content of conjunctival epithelium appears to change as a result of the stresses of epithelial repair, the goblet cell population may reflect the presence of reparative or proliferative processes in the ocular surface.

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AnimalsCell DifferentiationCell DivisionConjunctivaEpithelial CellsRabbitsWound HealingJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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H S Geggel, J Friend, R A Thoft. 1984. Conjunctival epithelial wound healing.. https://pubmed.ncbi.nlm.nih.gov/6735650/

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