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PubMed · 6738289

[Clinical studies using a photometric method for determining serum lipase activity].

W Bornschein
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Abstract

Results of measurement of serum lipase activity as determined by a UV-test described by Myrick and a titrimetric assay as described by Rick were compared as far as sensitivity and specificity in diagnosis of pancreatitis is concerned. Sensitivity of the UV assay is low (45% falsely normal values), and specificity as well (falsely pathological values in 55.5% of patients with liver disease and 9% of normal persons). In the UV assay lipoproteinlipases are measured as well as hepatic esterases: in 17 samples from persons having received heparin lipase activity was increased 3-8 fold. In a total of 99 samples no correlation was found between the results of the 2 assays. As a consequence it can be stated that the UV-test as described by Myrick has no relevance in diagnosis of pancreatitis; the commercially available assay kit is withdrawn in the meantime.

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HumansLipaseLiver DiseasesPancreatic DiseasesPhotometryEnglish AbstractJournal Article

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W Bornschein. 1984. [Clinical studies using a photometric method for determining serum lipase activity].. https://pubmed.ncbi.nlm.nih.gov/6738289/

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