Pathophysiological correlates in bacterial meningitis.

W M Scheld

doi:10.1016/s0163-4453(81)80003-5

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Pathophysiological correlates in bacterial meningitis.

W M Scheld

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Abstract

This review summarises briefly several areas of importance in the pathogenesis of bacterial meningitis. These subjects include: (1) factors that predispose to the development of disease and relevant host defense mechanisms; (2) microbial virulence factors; (3) the route(s) of entry for bacteria into the cerebrospinal fluid (CSF); (4) the role of pathological changes in the central nervous system; (5) particulate clearance mechanisms operative in the CSF system; and (6) the physiological alteration in normal intracranial homeostatic processes.

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Animals Bacterial Infections Blood-Brain Barrier Cerebrospinal Fluid Humans Immunity, Innate Meningitis Permeability Virulence Journal Article Review

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W M Scheld. 1981. Pathophysiological correlates in bacterial meningitis.. https://doi.org/10.1016/s0163-4453(81)80003-5

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