Clinical trials: some reflections.

W W Holland; E Breeze; A V Swan

doi:10.1002/sim.4780010414

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Clinical trials: some reflections.

W W Holland·E Breeze·A V Swan

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Abstract

The principles and historical development of clinical trials are outlined briefly. Some issues that extend the basic philosophy first put forward by Sir Austin Bradford Hill 40 years ago and that will need consideration in the future application of clinical trials are discussed.

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W W Holland, E Breeze, A V Swan. Clinical trials: some reflections.. https://doi.org/10.1002/sim.4780010414

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