Electronic properties of the nitrosamine function.

R E Lyle; H M Fribush; G G Lyle; J E Saavedra

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PubMed · 680749

Electronic properties of the nitrosamine function.

R E Lyle·H M Fribush·G G Lyle·J E Saavedra

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Abstract

The addition of a chiral alcohol, such as l-menthol or R-(-)-2-octanol, to an achiral nitrosamine causes a dissymmetric perturbation of the symmetrical chromophore and a Cotton effect is evident in the circular dichroism curve at the wavelength of ultraviolet absorption of the nitrosamine function. The intensity (ellipticity) of this induced circular dichroism is concentration dependent and appears to result from a weak 1:1 complex of nitrosamine and alcohol. The implications of these observations for structural studies are considered.

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Chemical Phenomena Chemistry, Physical Circular Dichroism Menthol Molecular Conformation Nitrosamines Journal Article Research Support, U.S. Gov't, P.H.S.

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R E Lyle, H M Fribush, G G Lyle, J E Saavedra. 1978. Electronic properties of the nitrosamine function.. https://pubmed.ncbi.nlm.nih.gov/680749/

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