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Oral tonsils: an immunoperoxidase study.

J B Matthews·M K Basu
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Abstract

Tissue morphometry and the distribution of cells containing immunoglobulin (Ig), J chain and secretory component (SC) were studied in eight oral tonsils. Quantitative immunohistochemistry revealed that IgG-containing cells predominated in all lymphoid compartments (follicles, extrafollicular areas and reticular epithelium) and that the IgG:IgA:IgM class ratios of the overall tonsillar immunocyte population were 13:8:2. Cells containing IgD and IgE were rare. IgG immunocytes showed no significant localisation within a given lymphoid compartment, whereas IgA cells were found predominantly in extrafollicular areas, especially adjacent to surface epithelium, and IgM cells were in follicles. J chain was present within IgM and some IgA cells. Tonsillar crypt and surface epithelium was negative for SC, suggesting that these structures are not directly involved in local mucosal immunity.

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HumansImmunoenzyme TechniquesImmunoglobulin AImmunoglobulin GImmunoglobulin J-ChainsImmunoglobulin MPalatine TonsilPlasma CellsSecretory ComponentJournal Article

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J B Matthews, M K Basu. 1982. Oral tonsils: an immunoperoxidase study.. https://doi.org/10.1159/000233140

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