[Comparative analysis in assessing the thyroliberin test in thyroid function disorders].

Abstract

The thyroliberine test was performed in 128 subjects with euthyroidism, thyrotoxicosis and initial hypothyrosis, using a "Hoechst" (FRG) drug in a dose of 200 micrograms, injected intravenously before and 30 minutes after thyroliberine administration, followed by radioimmunoassay of thyreotropic hormone. The test results were evaluated according to the difference and ratio of stimulated basal thyrotropin levels. Distribution of random errors of these findings was studied. Examination of a statistical hypothesis on the normal law of propagation of errors was realized according to the X2 criterion. It was detected that the introduction of a new index for the test evaluation is of interest, i.e. logarithm of ratio between stimulated and basal thyrotropin levels, which was the best one in the thyroid function increase. In initial hypothyrosis the use of the difference between stimulated and basal thyrotropin levels is more informative.