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PubMed · 6830594

Temperature dependent conformational changes in calmodulin.

P Gangola·H C Pant
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Abstract

Calcium bound calmodulin undergoes a reversible conformational change in the temperature range (22-28 degrees C). The transition temperature depends upon the concentration of calcium bound to calmodulin. The transition occurs at higher temperature (28 degrees C) in fully Ca2+ bound calmodulin as compared to those with lower Ca2+ concentrations (22 degrees C). The sequence of filling the four Ca2+ binding sites is different for the two temperature dependent conformers.

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Binding SitesCalciumCalcium-Binding ProteinsCalmodulinProtein ConformationSpectrometry, FluorescenceTemperatureJournal Article

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BibTeXRIS

P Gangola, H C Pant. 1983-02-28. Temperature dependent conformational changes in calmodulin.. https://doi.org/10.1016/s0006-291x(83)80151-x

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