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PubMed · 6832891

9-Fluorenylmethyl esters.

M A Bednarek·M Bodanszky
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Abstract

N alpha-Protected amino acid 9-fluorenylmethyl esters (Fm esters) were prepared by imidazole-catalyzed transesterification of active esters with 9-fluorenylmethanol (9-hydroxymethylfluorene). The new carboxyl protection is unaffected by acids, but is efficiently removed by beta-elimination under the influence of secondary and tertiary amines. Primary amines and ammonia can cause slight amide formation. Deblocking was achieved also by catalytic hydrogenation.

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EstersFluorenesIndicators and ReagentsOligopeptidesOptical RotationStructure-Activity RelationshipJournal ArticleResearch Support, Non-U.S. Gov't

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BibTeXRIS

M A Bednarek, M Bodanszky. 1983. 9-Fluorenylmethyl esters.. https://doi.org/10.1111/j.1399-3011.1983.tb03093.x

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