Antibody-induced cell-cycle synchrony.

M L Reid; J Marbrook

doi:10.1016/0008-8749(83)90384-2

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Antibody-induced cell-cycle synchrony.

M L Reid·J Marbrook

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Abstract

Synergism between specific antibodies and cytotoxic drugs in killing tumor cells is an established phenomenon. When cells grown in a suspension culture are treated with antibody, a subsequent increase in susceptibility to cytosine arabinoside has been shown to be due to the induction of cell-cycle synchrony. This observation may lead to a novel way of investigating cell-cycle-dependent processes and also an aspect of tumor-antibody interactions that is not generally recognized.

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Animals Antibodies, Neoplasm Cell Cycle Cells, Cultured Cytarabine Immunotherapy Mice Neoplasms, Experimental Journal Article Research Support, Non-U.S. Gov't

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M L Reid, J Marbrook. 1983. Antibody-induced cell-cycle synchrony.. https://doi.org/10.1016/0008-8749(83)90384-2

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