Endogenous opiates mediate radiogenic behavioral change.

G A Mickley; K E Stevens; G A White; G L Gibbs

doi:10.1126/science.6857244

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PubMed · 6857244

Endogenous opiates mediate radiogenic behavioral change.

G A Mickley·K E Stevens·G A White·G L Gibbs

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Abstract

Exposure of C57BL/6J mice to ionizing radiation caused stereotypical locomotor hyperactivity similar to that produced by morphine. Naloxone administration prevented this radiation-induced behavioral activation. These results support the hypothesis that endorphins are involved in some aspects of radiogenic behavioral change.

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Animals Behavior, Animal Dose-Response Relationship, Radiation Endorphins Male Mice Mice, Inbred C57BL Motor Activity Naloxone Journal Article Research Support, U.S. Gov't, Non-P.H.S.

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G A Mickley, K E Stevens, G A White, G L Gibbs. 1983-06-10. Endogenous opiates mediate radiogenic behavioral change.. https://doi.org/10.1126/science.6857244

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