Preconditioning for moisture control in ethylene oxide sterilization.

J B Murtaugh; G Whitaker

PubMed · 6877126

Preconditioning for moisture control in ethylene oxide sterilization.

Abstract

The moisture condition of a product must be controlled to obtain sterility and maintain product viability during ethylene oxide sterilization. A sterilization process in which prehumidification of product is used to provide moisture condition control was shown to be effective in 2 years of production sterilization experience. On-stream process analysis with a gas chromatograph showed that addition of steam to the chamber was unnecessary when properly preconditioned medical devices packaged in corrugated paper-board were sterilized. Reproducible gas-chamber moisture control and microbial sterility assurance were obtained.

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Catheters, Indwelling Chromatography, Gas Consumer Product Safety Ethylene Oxide Humans Humidity Quality Control Sterilization Time Factors Journal Article

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J B Murtaugh, G Whitaker. Preconditioning for moisture control in ethylene oxide sterilization.. https://pubmed.ncbi.nlm.nih.gov/6877126/

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