Purification from starfish eggs of a protein that depolymerizes actin.

I Mabuchi

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PubMed · 6894753

Purification from starfish eggs of a protein that depolymerizes actin.

I Mabuchi

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Abstract

A protein which is capable of depolymerizing F-actin was purified from an extract of unfertilized starfish eggs by the use of DEAE-cellulose column chromatography and hydroxylapatite column chromatography. This protein has an apparent molecular weight of 17,000. It inhibited the extent of actin polymerization as well as depolymerizing F-actin rapidly. It was shown that this protein reacts with actin at a molar ratio of 1 : 1. The properties of this protein were compared with those of profilin from mammalian tissues.

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Actins Animals Chromatography, DEAE-Cellulose Chromatography, Gel Egg Proteins Female Molecular Weight Ovum Starfish Journal Article Research Support, Non-U.S. Gov't

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I Mabuchi. 1981. Purification from starfish eggs of a protein that depolymerizes actin.. https://pubmed.ncbi.nlm.nih.gov/6894753/

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