PubMed · 6923252
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C Blakeney. Therapeutic embolisation.. https://pubmed.ncbi.nlm.nih.gov/6923252/
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Therapeutic embolization of blood vessels is widely used to treat vascular malformations and to preoperatively decrease the size of bulky tumors by creating iatrogenic infarction. Surgical pathologists are often called upon to identify the presence of embolized material in microscopic slides. Polyvinyl alcohol particles are often used as the material for embolization. On hematoxylin-eosin and other routine stains this substance is almost invisible. These particles stain black and can be sharply outlined by using the Verhoeff-Van Gieson stain.
Splenic vein thrombosis is a complication of pancreatic carcinoma or pancreatitis. It may lead to gastric varices which are difficult to treat and splenectomy may be required to stop variceal bleeding. A case of bleeding gastric varices secondary to splenic vein thrombosis and successfully treated by splenic artery embolization is reported. Embolization was performed by transcatheter deposition of four Gianturco coils into the splenic artery. This resulted in reduced blood flow through the spleen with partial splenic infarction and cessation of variceal bleeding. There has been no recurrence of bleeding in the 6 months since the procedure. Literature review confirms that experience of using this treatment is very limited and it should therefore be restricted to patients at high risk from surgery.