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PubMed · 6929968

Subclinical hypothyroidism.

M S Croxson·H K Ibbertson
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Abstract

Clinical and biochemical indices of thyroid function were compared in 18 euthyroid control subjects and 54 patients at risk of developing hypothyroidism, and the assessment repeated after a four-week trial of oral triiodothyronine (T3) 40 microgram daily. Patients with minor elevation of the pre-treatment serum TSH concentration (5-15 microU/ml) showed significant reduction in the free thyroxine index (FTI), prolongation of the basal ankle reflex half-relasation time (ART), and shortening of the ART after oral T3 treatment, when compared either to control subjects or to patients with a normal TSH level. It is concluded that patients with minimal TSH elevation have minor but parallel abnormalities of both thyroid hormone concentration and action.

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HumansHypothyroidismThyroid Function TestsThyroid HormonesThyrotropinTriiodothyronineJournal Article

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M S Croxson, H K Ibbertson. 1980-02-13. Subclinical hypothyroidism.. https://pubmed.ncbi.nlm.nih.gov/6929968/

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