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PubMed · 6930661

Chromatin repeat length in somatic hybrids.

L Sperling·A Tardieu·M C Weiss
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Abstract

In order to study the mechanisms by which a characteristic repeat length is inherited in somatic cells, it was necessary to develop a method for determining repeat length with a precision of 1 to 2 base pairs. Hybrid clones between parental cell lines differing in repeat length by 6 base pairs were isolated. The four independent hybrid clones characterized had repeat lengths intermediate between those of the parental lines; however, it could be demonstrated that these repeat lengths are unique values and do not arise from a double distribution of the parental repeat lengths. It therefore is concluded that repeat length in somatic cells is determined by a common pool of diffusible substances.

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AnimalsBinding SitesChromatinDNAHistonesHybrid CellsKaryotypingMicrococcal NucleaseMolecular WeightNucleosomesRatsJournal Article

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L Sperling, A Tardieu, M C Weiss. 1980. Chromatin repeat length in somatic hybrids.. https://doi.org/10.1073/pnas.77.5.2716

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