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PubMed · 6972149

Precursor T cell leukemia--immunological, cytochemical and morphological studies.

T Morita·R Morita·S Takagi·N Shimoyama·K Nagai
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Abstract

A case of acute lymphoblastic leukemia with a giant splenomegaly in an 8-year-old boy was investigated by immunological, cytochemical and electronmicroscopical techniques. Bone marrow and peripheral blood were largely replaced by large blast cells with a nonconvoluted nucleus. Cytochemically, most of the blast cells showed strong focal acid phosphatase activity. In the surface marker studies, these blast cells formed EAC rosettes but not E rosettes, while they showed positive reactivity with anti-T lymphocyte serum but not with anti-B lymphocyte serum. This membrane phenotype E-, C3R+, T+, B- suggested that leukemic blast cells in this patient presumably originated from precursor T cells.

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Acid PhosphataseBone MarrowChildHistocytochemistryHumansMalePrecursor T-Cell Lymphoblastic Leukemia-LymphomaT-LymphocytesCase ReportsJournal Article

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T Morita, R Morita, S Takagi, N Shimoyama, K Nagai. 1981. Precursor T cell leukemia--immunological, cytochemical and morphological studies.. https://pubmed.ncbi.nlm.nih.gov/6972149/

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