[Mechanism of the decrease in basal metabolism during adaptation to hypoxia].

F Z Meerson; A F Bogomolov

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PubMed · 698368

[Mechanism of the decrease in basal metabolism during adaptation to hypoxia].

F Z Meerson·A F Bogomolov

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Abstract

Oxygen uptake fell by 40% in rat adaptation to the periodic action of hypoxia under conditions of pressure chamber. This phenomenon did not disappear in animals in the state of profound anesthesia, and, consequently, was independent of adaptation changes of the cortical regulation of the animal motor activity. A cut of oxygen uptake by half persisted with the action of cold, noradrenaline, and 2,4-dinitrophenol, uncoupling oxidation and phosphorylation, on the organism. Thus, economic expenditure of oxygen in hypoxia adaptation could not be fully explained by increase of oxydation and phosphorylation conjugation.

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Adaptation, Physiological Anesthesia, General Animals Basal Metabolism Cold Temperature Dinitrophenols Female Hypoxia Norepinephrine Oxygen Consumption Rats Thiopental Journal Article

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F Z Meerson, A F Bogomolov. 1978. [Mechanism of the decrease in basal metabolism during adaptation to hypoxia].. https://pubmed.ncbi.nlm.nih.gov/698368/

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