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PubMed · 6991651

A computerized alert program for acutely ill patients.

D S Johnson·J Ranzenberger·R D Herbert·R M Gardner·T P Clemmer
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Abstract

An integrated computer system with a central data-base and decision-making capabilities is the basis of an investigation of a computerized alerting program that rapidly detects, analyzes, and generates diagnostic interpretations and treatment protocols for life-threatening laboratory abnormalities. Preliminary study data suggests that use of the alerting program to promptly notify physicians of abnormal laboratory values results in more prompt and correct treatment of patients.

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Acute DiseaseDiagnosis, Computer-AssistedFemaleHospitalsHumansInformation SystemsMiddle AgedUtahCase ReportsJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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D S Johnson, J Ranzenberger, R D Herbert, R M Gardner, T P Clemmer. 1980. A computerized alert program for acutely ill patients.. https://doi.org/10.1097/00005110-198006000-00005

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Acute spermatic cord torsion alters the microcirculation of the contralateral testis.

PURPOSE: The purpose of this study was to characterize the hemodynamic changes in the contralateral testis during acute spermatic cord torsion in anesthetized rats. MATERIALS AND METHODS: We used videomicroscopy to examine the microcirculation of the contralateral testis following acute torsion. Specifically, we examined the effect on vasomotion, a rhythmic dilation and constriction of the arterioles that is involved in fluid and nutrient exchange and modulation of local vascular resistance. In a separate set of experiments, blood flow in the contralateral internal spermatic artery was measured with an ultrasonic flow probe during acute torsion. RESULTS: Following 720 degrees torsion, the amplitude of vasomotion in the contralateral testis increased 121% (29.0 +/- 3.9% versus 13.0 +/- 1.7%) compared with controls. Blood flow in the contralateral internal spermatic artery decreased 43% after 2 hours' torsion. CONCLUSIONS: Acute spermatic cord torsion altered the microcirculation by increasing the amplitude of vasomotion and decreased total blood flow to the opposite testis. Because the hydraulic resistance of a blood vessel exhibiting vasomotion is always less than a vessel with the same average but static diameter, the observed microcirculatory changes may be an adaptive response to preserve local flow in the presence of decreased total flow. The long-term consequences of these changes in the microcirculation may affect testicular function and ultimately fertility.

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