Surface antigen on Ehrlich ascites tumor cells.

A Pessina; P Brambilla; P Mocarelli

PubMed · 7000194

Surface antigen on Ehrlich ascites tumor cells.

Abstract

Ehrlich Ascites Tumor (EAT) may be regarded as an extreme example of a reduced expression of normal histocompatibility antigens which is also reflected in its ability to grow in almost any mouse strain. In this report we discuss some evidence about a specific antigenicity detected on the cell surface of EAT strain maintained by serial transfer in C57BL/6 mice. The antiserum against EAT antigen was prepared by immunizing rabbits with an extract obtained by KCl treatment of EAT cells and then tested for cytotoxicity on EAT cells. The specificity, confirmed by using the indirect immunofluorescence test and the inhibition of cytotoxicity by EAT antigen, was also discussed.

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Animals Antigens, Neoplasm Antigens, Surface Carcinoma, Ehrlich Tumor Cytotoxicity, Immunologic Dose-Response Relationship, Immunologic Female Fluorescent Antibody Technique Immune Sera Mice Journal Article Research Support, Non-U.S. Gov't

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A Pessina, P Brambilla, P Mocarelli. Surface antigen on Ehrlich ascites tumor cells.. https://pubmed.ncbi.nlm.nih.gov/7000194/

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