Yeast viral RNA polymerase is a transcriptase.

J Bruenn; L Bobek; V Brennan; W Held

doi:10.1093/nar/8.13.2985

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Yeast viral RNA polymerase is a transcriptase.

J Bruenn·L Bobek·V Brennan·W Held

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Abstract

ScV-L is a simple double-stranded RNA virus of yeast, consisting of a 4.8 kilobase pair double-stranded RNA (L) encapsidated in isometric particles composed mainly of one polypeptide (ScV-Pl) of 88,000 daltons. L encodes ScV-Pl. There is a capsid-associated RNA polymerase that synthesizes in vitro predominantly single-stranded RNA. We show that this polymerase activity is a transcriptase, at the least one product of which is the mRNA for ScV-Pl. The transcript, like its template, is uncapped.

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DNA-Directed RNA Polymerases Nucleic Acid Hybridization Protein Biosynthesis RNA, Double-Stranded Saccharomyces cerevisiae Templates, Genetic Transcription, Genetic Viruses Journal Article Research Support, U.S. Gov't, P.H.S.

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J Bruenn, L Bobek, V Brennan, W Held. 1980-07-11. Yeast viral RNA polymerase is a transcriptase.. https://doi.org/10.1093/nar%2F8.13.2985

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