Structure-function relationships in insulin.

D J Saunders

doi:10.1007/bf01121582

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PubMed · 7028158

Structure-function relationships in insulin.

D J Saunders

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Abstract

A new interpretation of structure-function relationships in the insulin molecule is presented. Negative cooperativity is postulated to arise from a dimerization event occurring between two receptor-bound molecules. The receptor-binding surface of insulin can necessarily not involve residues involved in dimerization as has been generally accepted. Support for this interpretation is based on published data.

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Chemical Phenomena Chemistry Insulin Models, Chemical Receptor, Insulin Structure-Activity Relationship Journal Article Research Support, Non-U.S. Gov't

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D J Saunders. 1981. Structure-function relationships in insulin.. https://doi.org/10.1007/bf01121582

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