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Human amniotic fluid alpha-glucosidase.

L Poenaru·M C Vinet·J C Dreyfus
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Abstract

Amniotic fluid in midpregnancy contains significant alpha-glucosidase activity. This enzyme is distinguishable from the lysosomal acid alpha-glucosidase, deficiency of which is associated with Pompe's disease. The two enzymes differ in optimum pH, thermal stability, electrophoretic migration, isoelectric point, molecular mass, and immunological response. Amniotic alpha-glucosidase is also different from the classical neutral form. Immuno-cross reactions suggest that the amniotic fluid enzyme has a double fetal origin: renal and intestinal. It seems that alpha-glucosidase in amniotic fluid is linked to lipids.

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Amniotic FluidElectrophoresisFemaleGlucosidasesHot TemperatureHumansHydrogen-Ion ConcentrationImmune SeraIsoelectric FocusingMolecular WeightPregnancyalpha-GlucosidasesJournal ArticleResearch Support, Non-U.S. Gov't

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L Poenaru, M C Vinet, J C Dreyfus. 1981-11-25. Human amniotic fluid alpha-glucosidase.. https://doi.org/10.1016/0009-8981(81)90009-7

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