Comparison of ruminant anthelmintics, using multiple dose administration.

D K Hass; E L Holloway; L J Brown

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PubMed · 7073071

Comparison of ruminant anthelmintics, using multiple dose administration.

D K Hass·E L Holloway·L J Brown

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Abstract

Eleven ruminant anthelmintics were administered to lambs over a 30-day period, using medicated feeds or multiple oral doses. Fenbendazole and its sulfinyl analog, oxfendazole, were effective (greater than 90%) in the control of clinical parasitism at feeding levels of 5 mg/kg of feed. Parbendazole and albendazole were effective at daily oral dose levels of 1 mg/kg of body weight and at feeding dose levels of 10 mg/kg of feed, respectively. Levamisole, mebendazole, and oxibendazole were ineffective in controlling intense natural parasitic infections of sheep at daily oral dose levels equal to or less than 1 mg/kg of body weight and/or a feeding level equal to or less than 10 mg/kg of feed.

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Animals Anthelmintics Benzimidazoles Carbamates Drug Resistance Drug Therapy, Combination Fenbendazole Helminthiasis Helminthiasis, Animal Sheep Sheep Diseases Journal Article

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D K Hass, E L Holloway, L J Brown. 1982. Comparison of ruminant anthelmintics, using multiple dose administration.. https://pubmed.ncbi.nlm.nih.gov/7073071/

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