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PubMed · 7089757

Free thyroxine or free thyroxine index?

J L Miller·J Smith
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Abstract

Free thyroxine (FT4) values determined by direct radio-immunoassay and the free thyroxine index (FTI) determined by indirect calculation were compared in 431 consecutive sera from patients with suspected thyroid dysfunction . Sensitivity and specificity were similar for both tests in the thyrotoxic, hypothyroid and euthyroid ranges with appropriate thyroid-binding globulin (TBG) concentrations. However, FT4 was superior to FTI in the euthyroid group with high concentrations of TBG, FT4 is therefore a useful alternative to FTI as a screening test for thyroid dysfunction, and is likely to be a better discriminator of thyroid status in patients with high TBG levels.

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Evaluation Studies as TopicHumansRadioimmunoassayReagent Kits, DiagnosticThyroid DiseasesThyroxineComparative StudyJournal ArticleResearch Support, Non-U.S. Gov't

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J L Miller, J Smith. 1982-06-12. Free thyroxine or free thyroxine index?. https://pubmed.ncbi.nlm.nih.gov/7089757/

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