PubMed · 7133609
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E Davidoff, J Duggan. 1982. A loading guide for C-loop intraocular lenses.. https://pubmed.ncbi.nlm.nih.gov/7133609/
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PURPOSE: To compare the light transmittance of 4 currently marketed intraocular lenses (IOLs) with that of the new AcrySof Natural IOL (Alcon Laboratories, Inc.), which is designed to mimic the light-attenuating characteristics of the human crystalline lens. SETTING: Research laboratory, Alcon Research, Ltd., Fort Worth, Texas, USA. METHODS: Light-transmission spectra of 4 commonly implanted IOLs were compared with the spectrum of the AcrySof Natural IOL (model SN60AT). RESULTS: While the 4 other foldable IOLs transmitted nearly 100% (near 0% absorption) of the light in the 400 to 500 nm (blue-light) region, the AcrySof Natural IOL absorbed a significant portion of blue light. Comparison of the spectrum of the AcrySof Natural IOL with the spectrum of human crystalline lenses of various ages showed that the AcrySof Natural lens closely mimics the light-attenuating characteristics of the human crystalline lens. CONCLUSIONS: The AcrySof Natural IOL provides a transmission spectrum more like that of a human crystalline lens than do other commonly implanted foldable IOLs. The Natural IOL reduces ultraviolet and blue-light exposure to the retina, mimicking the filtering normally provided by the human crystalline lens.
PURPOSE: To compare the shape recovery ratios after compression of haptic materials used in the manufacture of intraocular lenses (IOLs). SETTING: Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. METHODS: The loop memory of 40 silicone-optic posterior chamber IOLs was studied. All the IOLs had modified-C haptics made of poly(methyl methacrylate) (PMMA; n = 10), polyimide (n = 10), polyvinylidene fluoride (PVDF; n = 10), and polypropylene (PP; n = 10). After the overall diameter of each lens was measured (day 0), the lenses were inserted into plastic wells (9.5 mm in diameter) and immersed in water (37 degrees C) for 1 month. They were then placed on an open plate and allowed to reexpand for 2 months. Overall diameter measurements were performed within 5 minutes of the IOLs' removal from the wells and at subsequent time points (days 14, 28, 30, 60, 74, 88, and 95). RESULTS: The loop memory of each lens was expressed as the difference between the initial overall diameter measurement (pretest) and the measurement at each time point; the lower the value, the higher the memory. The overall difference among the 4 groups was statistically significant at each time point (P < or = .001). From days 30 to 95, silicone-PMMA, silicone-elastimide, and silicone-PVDF IOLs had similar loop memory mean values, which were significantly lower than the mean value of silicone-PP IOLs (P <.05). The latter design tended to be deformed after removal from the wells, with increased optic-haptic angulation. CONCLUSION: Studying the loop memory of haptic materials (PMMA, polyimide, PVDF, and PP) used in the manufacture of posterior chamber IOLs can help surgeons choose an appropriate IOL for each patient.
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