PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 7140338

Helium meter correction equations for oxygen and nitrous oxide.

R E Justice·B J Kripke·H B Hechtman
View original source ↗Export metadata ↓

Abstract

Helium detectors utilizing thermal conductivity are sensitive to the presence of nitrous oxide (N2O) and oxygen (O2). Measurement of the level of these gases within the spirometer may be used to obtain the true helium concentration for use in the calculation of functional residual capacity (FRC). Linear relationships were obtained relating the change (delta) in reading of the helium meter by nitrous oxide and oxygen. The regression equations are: delta O2 = 0.027 (%O2) - 0.513; delta N2O = -0.276 (%N2O). Failure to correct the helium reading for N2O will overestimate lung volume; elevations of O2 above 21% will underestimate the lung volume.

Explore related subjects

HeliumHumansMathematicsNitrous OxideOxygenSpirometryJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

R E Justice, B J Kripke, H B Hechtman. 1982. Helium meter correction equations for oxygen and nitrous oxide.. https://doi.org/10.1097/00003246-198212000-00015

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

Advances in magnetic resonance imaging of lung physiology.

This review presents an overview of some recent magnetic resonance imaging (MRI) techniques for measuring aspects of local physiology in the lung. MRI is noninvasive, relatively high resolution, and does not expose subjects to ionizing radiation. Conventional MRI of the lung suffers from low signal intensity caused by the low proton density and the large degree of microscopic field inhomogeneity that degrades the magnetic resonance signal and interferes with image acquisition. However, in recent years, there have been rapid advances in both hardware and software design, allowing these difficulties to be minimized. This review focuses on some newer techniques that measure regional perfusion, ventilation, gas diffusion, ventilation-to-perfusion ratio, partial pressure of oxygen, and lung water. These techniques include contrast-enhanced and arterial spin-labeling techniques for measuring perfusion, hyperpolarized gas techniques for measuring regional ventilation, and apparent diffusion coefficient and multiecho and gradient echo techniques for measuring proton density and lung water. Some of the major advantages and disadvantages of each technique are discussed. In addition, some of the physiological issues associated with making measurements are discussed, along with strategies for understanding large and complex data sets.

Helium↗
PubMed2006

Optical pumping system design for large production of hyperpolarized.

We present a design for a spin-exchange optical pumping system to produce large quantities of highly polarized 129Xe. Low xenon concentrations in the flowing gas mixture allow the laser to maintain high Rb polarization. The large spin-exchange rate between Rb and 129Xe through the long-lived van der Waals molecules at low pressure, combined with a high flow rate, results in large production rates of hyperpolarized xenon. We report a maximum polarization of 64% achieved for a 0.3 l/h Xe flow rate, and maximum magnetization output of 6 l/h at 22% polarization. Our findings regarding the polarization dependence on temperature, nitrogen partial pressure, and gas mixture flow velocity are also reported.

Helium↗