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PubMed · 7155998

Paramunity after oral immunization.

H Raettig
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Abstract

Previously, we have proposed the term of paramunity which represented the whole nonspecific defence reactions. Now, we experimentally have demonstrated the importance of an oral polybacterial vaccine in the local defence of the intestine against Salmonella or an enterovirus. The role of interferon was also discussed.

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Administration, OralAnimalsBacterial VaccinesEnterobacteriaceae InfectionsEnterovirus InfectionsHumansImmunityImmunity, InnateImmunizationIntestinal DiseasesMiceMice, Inbred StrainsJournal Article

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H Raettig. 1982. Paramunity after oral immunization.. https://pubmed.ncbi.nlm.nih.gov/7155998/

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PubMed1996

A randomized crossover study using yohimbine and isoxsuprine versus pentoxifylline in the management of vasculogenic impotence.

PURPOSE: We evaluated the efficacy and safety of yohimbine and isoxsuprine or pentoxifylline in the management of vasculogenic erectile dysfunction. MATERIALS AND METHODS: A total of 20 patients diagnosed with arterial insufficiency and cavernous venous leakage by pharmacological penile duplex scanning underwent nonhormonal oral therapy. A randomized crossover study was performed using 5.4 mg. yohimbine plus 10 mg. isoxsuprine or 400 mg. pentoxifylline 3 times daily. Response to therapy was assessed by a sexual questionnaire and repeat penile duplex ultrasonography. RESULTS: No patient in either phase of the study in either group had a complete response to the oral regimen(s) and there was no improvement in the pre-injection or post-injection cavernous arterial peak systolic flow velocities or resistance indexes. CONCLUSIONS: Our study suggests that these oral agents, although well tolerated, were not effective in the management of these patients with mixed vasculogenic erectile dysfunction.

Administration, Oral↗