Double enkephalins.

A W Lipkowski; A M Konecka; B Sadowski

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PubMed · 7167423

Double enkephalins.

A W Lipkowski·A M Konecka·B Sadowski

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Abstract

Basing on the conclusions drawn from the biological activities of previously synthesized enkephalin analogues, a new class of enkephalin analogues named double-enkephalins have been proposed, in which C-terminal amino acid residue is replaced by a second active fragment of enkephalin analogue connected by diamine bridge. Guinea-pig ileum test showed high biological activity of proposed analogues but depending on the size of diamine bridges.

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Animals Binding Sites Enkephalins Guinea Pigs Ileum In Vitro Techniques Muscle Contraction Muscle, Smooth Structure-Activity Relationship Journal Article Research Support, Non-U.S. Gov't

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A W Lipkowski, A M Konecka, B Sadowski. 1982. Double enkephalins.. https://pubmed.ncbi.nlm.nih.gov/7167423/

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