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PubMed · 7176561

Improved detection and identification of basic drugs extracted from tissue using TLC.

L Galante·J Bonventre·H Salvione·M L Bastos
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Abstract

Improved separation of methaqualone, lidocaine, cocaine, phencyclidine, phenacetin and methadone was achieved by a double development technique using dichloromethane:methyl ethyl ketone:ammonia (90:10:1.5 and 30:70:2). Improved identification of spots for some basic drugs was achieved after the traditional detection spray sequence with successive topical applications of: Marquis reagent, Mandelin reagent and a special ammonium molybdate fuming sulfuric acid reagent.

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Chromatography, Thin LayerColorimetryForensic MedicineHumansLiverPharmaceutical PreparationsSolventsJournal Article

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L Galante, J Bonventre, H Salvione, M L Bastos. Improved detection and identification of basic drugs extracted from tissue using TLC.. https://doi.org/10.1093/jat%2F6.5.262

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