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PubMed · 7182110

Age associated decrease of N-acetyl-beta-glucosaminidase activity in the lens epithelial cells from C57Bl/6 mice.

R D Lipman·A L Muggleton-Harris
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Abstract

Lens epithelial cells were isolated from samples of C57BL/6 and CD-1 mice at different ages between 1 and 5 months, and assayed for the level of N-acetyl-beta-glucosaminidase and their ability to replicate in-vitro. The lens epithelial cells from C57BL/6 mice had a reduced replicative potential compared to other normal strains. A statistically significant decrease in active enzyme levels was demonstrated to be associated with increased animal age of C57BL/6 mice.

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AcetylglucosaminidaseAgingAnimalsEpithelial CellsFemaleHexosaminidasesLens, CrystallineMiceMice, Inbred C57BLMice, Inbred DBAJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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R D Lipman, A L Muggleton-Harris. Age associated decrease of N-acetyl-beta-glucosaminidase activity in the lens epithelial cells from C57Bl/6 mice.. https://doi.org/10.3109/02713688208996354

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