[Polycytidylic matrix complex formation with complementary and noncomplementary purine nucleoside triphosphates].

A S Gukovskaia; N M Gusenkova; V N Lanin; B I Sukhorukov

PubMed · 719039

[Polycytidylic matrix complex formation with complementary and noncomplementary purine nucleoside triphosphates].

A S Gukovskaia·N M Gusenkova·V N Lanin·B I Sukhorukov

Abstract

Misincorportion into I poly(C) : I GTP complex, alpha = (formula: see text), has been determined by using H3-ATP. At ATP total concentration increasing from 6X10(-6) M to 4.5X10(-3) M the alpha value increases going asymptotically onto a plateau. The maximum misincorporation in the studied conditions is I adenilic resiude per congruent to 1400 guanilic ones. No ATP incorporation into the 2 poly(C) : I GTP complex was found. It is shown that misincorporation in non-enzymic recognition is essentially determined both by the difference in complementary and non-complementary monomer stacking and by the difference in their binding with the polynucleotide template.

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Adenosine Triphosphate Chemical Phenomena Chemistry Guanosine Triphosphate Poly C Polyribonucleotides Comparative Study English Abstract Journal Article

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A S Gukovskaia, N M Gusenkova, V N Lanin, B I Sukhorukov. [Polycytidylic matrix complex formation with complementary and noncomplementary purine nucleoside triphosphates].. https://pubmed.ncbi.nlm.nih.gov/719039/

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