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PubMed · 7202829

A study of Campylobacter enteritis.

Abstract

During the years 1978 and 1979, 432 separate outbreaks of gastro-enteritis were reported to this department by the employees of this company. All these outbreaks were fully screened, and it was seen that nineteen employees had gastro-enteritis caused by Campylobacter organisms. Investigation of these employees revealed significant findings with regard to the possible human source of the organism, and leads us to conclude that the organism can be spread by human-to-human contact, and must be treated as a food poisoning organism with subsequent exclusion of food handlers from work during the period of carriage of the organism. The study also demonstrated that the illness suffered by the affected employees was severe in nature and lasted approximately 1 to 10 days. It took on average between 17 and 19 days during 1979 for clearance to occur in the specimens of the affected employees. Thus, if food handlers are excluded from work when affected, this is a considerable period of absence from work, with considerable cost to industry and the community.

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BibTeXRIS

A Jones, C Harrop. 1981. A study of Campylobacter enteritis.. https://doi.org/10.1177/030006058100900107

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Campylobacter jejuni infection and Guillain-Barré syndrome.

BACKGROUND: Although infection with Campylobacter jejuni is recognized as a common antecedent of the Guillain-Barré syndrome, the clinical and epidemiologic features of this association are not well understood. METHODS: We performed a prospective case-control study in a cohort of patients with Guillain-Barré syndrome (96 patients) or Miller Fisher syndrome (7 patients) who were admitted to hospitals throughout England and Wales between November 1992 and April 1994. Bacteriologic and serologic techniques were used to diagnose preceding C. jejuni infection. RESULTS: There was evidence of recent C. jejuni infection in 26 percent of the patients with Guillain-Barré or Miller Fisher syndrome, as compared with 2 percent of household controls and 1 percent of age-matched hospital controls (P < 0.001). Of the 27 patients with C. jejuni infection, 19 (70 percent) reported having had a diarrheal illness within 12 weeks before the onset of the neurologic illness. No specific serotypes were associated with Guillain-Barré syndrome. C. jejuni infection was slightly more common in men (P = 0.14) and was more likely to be associated with a pure motor syndrome and a slower recovery (P = 0.03). The patients with preceding C. jejuni infection were more likely to have acute axonal neuropathy or axonal degeneration in association with acute inflammatory demyelinating polyradiculoneuropathy, and they had greater disability after one year (P = 0.02). C. jejuni infection was significantly associated with a poor outcome even after correction for other factors associated with a poor prognosis. CONCLUSIONS: Infection with C. jejuni often precedes the Guillain-Barré syndrome and is associated with axonal degeneration, slow recovery, and severe residual disability.

Campylobacter Infections