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A method for the automated screening for hepatitis B surface antigen.

K Kunitomo·H Saji·S Yahara·T Hosoi
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Abstract

A reverse passive hemagglutination (RPHA-G) technique for the automated screening of hepatitis B surface antigen (HBsAg) on the Groupamatic 360 (Kontron International, Zürich, Switzerland) has been developed. It is more sensitive than manual RPHA (RPHA-M) and nearly as sensitive as radioimmunoassay (RIA); it detects 6 ng/ml of HBsAg, compared to 3 ng/ml by RIA and 25 ng/ml by RPHA-M. Although it is slightly inferior to the other two methods in respect of specificity, the incidence of false-positive reactions was only 0.34%. The test can also be performed manually without the Groupamatic.

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AutomationFalse Positive ReactionsHemagglutination TestsHepatitis B Surface AntigensHumansRadioimmunoassayComparative StudyJournal Article

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BibTeXRIS

K Kunitomo, H Saji, S Yahara, T Hosoi. 1980. A method for the automated screening for hepatitis B surface antigen.. https://doi.org/10.1111/j.1423-0410.1980.tb01860.x

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