PubMed · 721590
[Antibiotic prophylaxis in plastic reconstructive surgery].
Abstract
In plastic reconstructive surgery the use of prophylactic antibiotics is considered for wounds in which tissue trauma can not exactly be delineated as in gun shot wounds, bites, contusions; for extensive surgery lasting more than three hours in the oral area, with opening of the maxillary sinuses; when large foreign bodies are implanted; if there is massive intraoperative contamination and for patients with reduced antibacterial defence mechanisms. A principal factor leading to infection is reduced tissue oxygenation, which can be reversed by the use of benzopyrones as experimentally demonstrated.
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L Clodius. 1978. [Antibiotic prophylaxis in plastic reconstructive surgery].. https://pubmed.ncbi.nlm.nih.gov/721590/
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